Watch Keller Williams’ Grateful Grass Mash-Up Two Classics At Catskill Chill

first_imgThe Catskill Chill Music Festival made its debut in Lakewood, PA last weekend, bringing thousands of music fans – ChillFam – to the annual festival. Chill closed out the summer in fine fashion, with tons of great talents from the jam scene playing great sets.One of the hallmarks of Catskill Chill is always the collaborative nature of their offered performances. Whether it’s planned super jams or tributes, or unplanned guest appearances, the festival never fails to capture that family vibe. One of the best came during a set from Keller Williams’ Grateful Grass, who paid tribute to the Dead with a great set.In the video below, the medley starts with a progression that sounds like “They Love Each Other,” but Keller leads the vocals on “Cumberland Blues.” Eventually the band does go into “They Love Each Other,” closing out the run of these great Dead songs! Naturally, they call the song “They Cumberlove Each Other.”Watch it all go down below, courtesy of 215music.last_img read more

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Eddie Vedder Joins Tom Petty And The Heartbreakers, On This Day In 2006

first_imgIt was 14 years ago today that Pearl Jam’s Eddie Vedder joined forces with Tom Petty and The Heartbreakers in Denver, CO for a rendition of “The Waiting” from the rocker’s 1981 album Hard Promises. Over the years, Vedder and Petty have found themselves on stage together quite a few times, but this was certainly one of those memorable performances from the two rock legends. Check out video below, courtesy of Release Coalition:last_img

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New approach to severe bacterial infections and sepsis

first_imgBacterial infections that don’t respond to antibiotics are of rising concern, as is sepsis — the immune system’s last-ditch attack on infection that ends up being lethal itself. Reporting in Nature, researchers at Harvard-affiliated Boston Children’s Hospital describe new potential avenues for controlling both sepsis and the runaway bacterial infections that provoke it.Sepsis kills a quarter million people each year in the United States and is the largest killer of newborns and children worldwide. Like antibiotic-resistant infections, it has no good treatment. Through scrupulous experiments, scientists in Boston Children’s Program in Cellular and Molecular Medicine (PCMM) have uncovered the final cellular events necessary for both sepsis and stemming the bacterial attack.Recent research has shown that at any sign of bacterial invasion, protein complexes called inflammasomes are activated. This activation triggers a process called pyroptosis — the infected cells explode open, releasing bacteria as well as chemical signals that sound an immune alarm. But there’s a balance: Too urgent an alarm can trigger sepsis, causing fatal blood-vessel and organ damage.“The immune system is trying like hell to control the infection, but if the bacteria win out, the immune response can kill the patient,” explains Judy Lieberman, senior investigator on the study together with Hao Wu, also in the PCMM. “Most attempts to quiet the immune response haven’t worked in treating sepsis in the clinic, because the parts that trigger it haven’t been well understood.”“Because of widespread antibiotic resistance, we have to think about other strategies,” said Judy Lieberman, senior investigator. Photo courtesy of Boston Children’s HospitalOnce activated, inflammasomes activate enzymes called caspases that cut a molecule called gasdermin D in two. This cleavage unleashes gasdermin D’s active fragment, known as gasdermin-D-NT. But how this causes pyroptosis hasn’t been known.Lieberman, Wu, and their colleagues now show that gasdermin-D-NT packs a one-two punch. On the one hand, it perforates the membranes of the bacteria that are infecting cells and kills them. It also punches holes in the membrane of the host cell, causing pyroptosis — killing the cell and releasing bacteria and immune alarm signals. The team also found that nearby uninfected cells were left unscathed.Second, the team discovered that gasdermin-D-NT directly kills bacteria outside cells, including E. coli, S. aureus, and Listeria. In a dish, this happened quickly — within five minutes.The results need to be replicated in animal models of infection and sepsis, but Lieberman believes that understanding how gasdermin-D-NT works could be harnessed to help treat highly dangerous bacterial infections.“Because of widespread antibiotic resistance, we have to think about other strategies,” she says. “Since the fragment kills bacteria but not uninfected host cells, one can imagine injecting the fragment directly, especially to treat a localized infection involving antibiotic-resistant bacteria.”For sepsis, Lieberman speculates about ways of inhibiting or blocking gasdermin-D-NT, such as with antibodies or strategies targeting caspase enzymes.Xing Liu, Zhibin Zhang, and Jianbin Ruan are co-first authors on the paper. The study was funded by the National Institutes of Health.Savelast_img read more

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Sweet Sales.

first_imgOut on the farm this spring, the bottom fell out of the market for Vidalia onions, the one money crop John McDonald grows. In the city, many school students were looking forwardto a summer camp they couldn’t afford.Both hardships, though, were softened because the two groups, rural and urban, got together beforehand on a solution to each other’s challenge. Photo:  Shirley Williamson Photo: Shirley Williamson Lauren Jolly cuts shipping netting from around 25-pound bags of Vidalia onions for her 4-H club’s fund-raiser. Volunteer Charlie Griffin and some Columbia County 4-H’ers wait for the next customer to drive through the fund-raiser distribution space donated by a local bank.center_img Camp Discounts,’Six Flags’ TicketsWilliamson goes all-out to promote the sale.”We focus on how special Vidalia onions are and how the kids can earn money for a discounted or even free trip to camp (normally $160),” she said. “Other prizes include a Columbia County 4-H T-shirt and free Six Flags tickets.”The 4-H’ers sell Vidalia onion cookbooks, too — this year more than 400 of them. Every 4-H’er who sells anything gets a 4-H cup, pencil and sticker. Everyone who buys onions or a cookbook gets a letter of appreciation, storage tips and a few recipes. 4-H Fund-raiser”Each year our 4-H’ers sell Vidalia onions as a fund-raiser,” said Shirley Williamson, a University of Georgia Extension Service agent in suburban Columbia County.For Williamson, the annual sale funds her 4-H program and gets kids to camp who might otherwise be unable to go. For McDonald, the Columbia 4-H’ers and other clubs lock in profits.It’s a sweet deal for shoppers, too, though the cost is almost always higher than in stores. For the extra money, buyers: Help a youngster, most likely a relative or neighbor, learn about working, the value of money and striving toward goals. Help a worthy organization earn operating funds. Help themselves, because club-sale onions are the sweetest there are. Club-sale Onions a Sweet Success”We strive to do a perfect job with these onions,” McDonald said. “I know 100 percent is hard to achieve, but we shoot for it.”And it’s not just McDonald.”Probably half of our growers have some club sales,” said Reid Torrance, a Tattnall County Extension Service agent. Tattnall farmers grow more Vidalia onions than inany other Georgia county, and fund-raisers take about 10 percent of their crop.”They usually try to do a better job with club sales,” Torrance said. “They want to be sure they get the very best quality. Some of our growers pack fund-raiser onions in a different packing line.”McDonald typically overfills each bag, too. “We always give good weights,” he said. So the price per pound is always lower than it seems.Loyal CustomersGrowers say their fund-raiser partners are their most loyal customers. “I added one Alabama club this year,” McDonald said. “All of the others are long-term relationships.”McDonald grows 30 acres of onions in Treutlen County, a dozen or so miles from Vidalia. He sells less than a third of his crop through club sales. “I wish I could sell more through clubs,” he said.More than a dozen Georgia 4-H clubs have onion-sale fund-raisers. Columbia County 4-H’ers have sold McDonald Farm onions for eight years. The sale is successful every year.This year they sold nearly 11 tons of Vidalia onions.Vidalia Onion ClassesTo make sure their fund-raisers succeed, Williamson and 4-H program assistant Paula Poss teach agriculture-related classes in club meetings.In one of three such classes this year, they showed students three containers of soil. One held soil from McDonald Farm. Another had heavy-clay soil from their own county. The third contained a commercial topsoil mix.Asked to pick the best soil for Vidalia onions, the students almost always pick the rich-looking commercial soil. From there, the teachers go on to explain how this sweet Georgia crop grows.All that education is necessary, Williamson said. “Think about it,” she said. “You’re a 5th grader, and 4-H wants you to sell onions. Yuck! They don’t usually eat onions. They want to sell candy or cookies.”last_img read more

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Marriage equality debate: Craig raises polygamy

first_imgStuff.co.nz 2 Aug 2012If Parliament moves to make same-sex marriages legal, then “polygamous relationships need recognising as well”, says the leader of the Conservative Party . In a live discussion today, Labour MP Louisa Wall and Conservative Party leader Colin Craig went head to head on the issue of marriage equality. Wall is leading the Marriage (Definition of Marriage) Amendment Bill, which has sparked heated debate since it was pulled from the ballot last week. Craig made headlines when the bill was drawn, after he said it wasn’t “intelligent to pretend that homosexual relationships are normal”. During the live chat both sides aired a number of views, while fielding questions from readers. In response to one question on whether the bill would just end up creating “fresh injustices” discriminating toward polygamy, Craig said the bill would inevitably raise that issue. “Louisa and I agree that marriage just can’t be open on the basis of people loving each other, it’s a question of the right place to draw the line. “If we are going to be consistent, and love is all that matters, then we will have to accept polygamous relationships need recognising as well,” he said. But Wall disagreed, saying marriage was based on love, which was why gay and lesbian people wanted the same rights. “Marriage is the institution of two people who love each other committing themselves to a shared life together. This bill will not address polygamy or other forms of relationship.” Craig said he did not think New Zealand needed to change the existing law.http://www.stuff.co.nz/national/politics/7400965/Marriage-equality-debate-Craig-raises-polygamylast_img read more

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Tom Snape named DCF Program Director

first_imgLAWRENCEBURG, Ind. — Former WRBI News Director, Tom Snape, has been named Program Director at the Dearborn Community Foundation.According to the foundation, Snape, of Bright, brings experience to the Foundation as a professional in the field of communication and customer service.Snape follows Denise Sedler who spent more than 8 years in the role before accepting a position with Ivy Tech in Lawrenceburg.last_img

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Walmart releases plans to restrict the sale of guns and ammunition

first_imgBentonville, Ar. — Walmart has announced plans to stop selling guns or ammunition to people younger than 21. The retail giant says they will also remove toys and items that resemble assault-style weapons.Company officials released the following statement:“In light of recent events, we’ve taken an opportunity to review our policy on firearm sales. Going forward, we are raising the age restriction for purchase of firearms and ammunition to 21 years of age. We will update our processes as quickly as possible to implement this change.In 2015, Walmart ended sales of modern sporting rifles, including the AR-15. We also do not sell handguns, except in Alaska where we feel we should continue to offer them to our customers. Additionally, we do not sell bump stocks, high-capacity magazines and similar accessories. We have a process to monitor our eCommerce marketplace and ensure our policies are applied.We take seriously our obligation to be a responsible seller of firearms and go beyond Federal law by requiring customers to pass a background check before purchasing any firearm. The law would allow the sale of a firearm if no response to a background check request has been received within three business days, but our policy prohibits the sale until an approval is given.We are also removing items from our website resembling assault-style rifles, including nonlethal airsoft guns and toys. Our heritage as a company has always been in serving sportsmen and hunters, and we will continue to do so in a responsible way.”last_img read more

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Juventus swap deals for Pogba

first_img Tuttosport point out any combination of players that could be used in a deal for Pogba, starting with Douglas Costa, who has proved too unreliable and injury-prone for Maurizio Sarri. Alex Sandro has long been appreciated by Manchester United and is rated at over €50m, while they had fought with Juventus and lost in the race to free agents Ramsey and Rabiot. read also:Ramadan Kareem: Pogba , Salah, Ozil, others send out wishes to fans Pjanic is on the exit list after falling down the pecking order in Turin, struggling to fit into Sarri’s tactics, and could be ready for a new experience in the Premier League. FacebookTwitterWhatsAppEmail分享 Inter, Real Madrid and Paris Saint-Germain are again linked with a swoop for Pogba this week, as news filtered through from England that United were not going to activate the extension option on his contract. That makes a summer sale almost inevitable, but the coronavirus pandemic has hit transfer fees hard and we probably won’t see another €120m move quite so soon. Instead, exchanges are going to be the order of the day and Juventus have a catalogue of impressive players that Manchester United can flip through.Advertisement Promoted ContentWho Is The Most Powerful Woman On Earth?6 Incredibly Strange Facts About HurricanesWhat Happens To Your Brain When You Play Too Much Video Games?Thailand’s 10 Most Iconic LandmarksTop 7 Best Car Manufacturers Of All Time6 Stunning Bridges You’ll Want To See With Your Own EyesWhich Country Is The Most Romantic In The World?5 Of The World’s Most Unique Theme ParksEver Thought Of Sleeping Next To Celebs? This Guy Will Show You6 Most Breathtaking Bridges In The World8 Facts About Sasha Obama9 Facts You Should Know Before Getting A Tattoo Loading… Juventus have several players who could be used in an exchange for Paul Pogba, with Douglas Costa, Miralem Pjanic, Alex Sandro, Aaron Ramsey or Adrien Rabiot to Manchester United.last_img read more

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Podolski sets up Arsenal win

first_img Arsenal welcomed back defender Laurent Koscielny from injury while Sweden midfielder Kim Kallstrom made his first start since arriving on a deadline-day loan from Spartak Moscow. West Ham – without captain Kevin Nolan who failed a fitness test – made a bright start. First, Diame’s effort was charged down by Per Mertesacker before on-loan Milan winger Nocerino drilled in an angled shot which was blocked. Arsenal slowly got into a spell of possession, and a low centre from Podolski down the left was just inches away from being tapped home by Giroud as he arrived at pace into the six-yard box. On 15 minutes, Arsenal midfielder Tomas Rosicky, who missed the Wembley tie because of injury, was late on Andy Carroll and was cautioned. Diame then fired the ball over from five yards after a cutback from Carroll following a corner. Arsenal should have been ahead on 30 minutes. Cazorla collected a loose ball in midfield and then fed Giroud on the edge of the West Ham penalty area. The France forward beat the offside trap and took the ball in his stride, only to then try to flick the ball into the bottom left corner with the outside of his left boot and Adrian was able to get across to make the save. West Ham took the lead five minutes before the break. Nocerino darted down the Arsenal right and into the penalty area, and his near-post shot was saved by Wojciech Szczesny. Jarvis reacted first to nod home from close range. Arsenal looked for an immediate response as Kallstrom fired in an angled drive which Adrian pushed behind. The hosts were level on 44 minutes. Cazorla collected a poor clearance from Stewart Downing some 30 yards out, and fed Podolski in the left side of the West Ham box. The German spun his marker before drilling a low shot into the far corner. Arsenal went into the lead 10 minutes into the second half. Captain Vermaelen, deployed at left-back following injury to Kieran Gibbs and Nacho Monreal, lobbed a deep pass from the halfway line into a crowded penalty area. Both Reid and Carroll tried to block the France forward, who showed superb strength and then a sublime touch to kill the ball dead, before coolly slotting past the keeper with his right foot. Adrian was called into action again on 61 minutes when he palmed away a curling free-kick from Podolski before Cazorla shaved the outside of the woodwork after cutting inside following a break down the right. With 20 minutes left, Rosicky was replaced by Aaron Ramsey, just back from a long injury lay-off. The Wales midfielder helped set up Arsenal’s third goal on 78 minutes when he nodded Giroud’s pass from the right through to Podolski, who turned to drill another fine finish past Adrian from 10 yards to wrap up victory. While the manner of this response will have pleased Wenger, the Gunners boss knows there is still much work to do if they are to secure another shot at elite European football ahead of their Wembley trip on May 17 – which continues at FA Cup final opponents Hull on Easter Sunday. Another powerful strike from Podolski with 13 minutes left secured all three points which saw Arsene Wenger’s side leapfrog Everton, who host Crystal Palace on Wednesday night. West Ham, who had not played since the home defeat to Liverpool on April 6, started well as Mohamed Diame fired a good chance over from close range on 18 minutes. Arsenal’s big chance arrived on the half-hour mark when Santi Cazorla latched on to a stray pass in midfield and then fed Giroud, who beat the offside trap, but his scuffed finish was saved at full stretch by Adrian. It proved costly as West Ham went ahead when Jarvis headed in from close range after Antonio Nocerino’s shot was saved at the near post. Arsenal, though, were level just before half-time as Podolski spun in the West Ham penalty area to drill a low shot into the bottom corner. Giroud finally showed the perfect touch to put Arsenal ahead 10 minutes into the second half. Thomas Vermaelen sent a high ball into the West Ham box, where Giroud held off both Winston Reid and Andy Carroll to take it down with one sublime left-foot touch before rolling his shot between the goalkeeper’s legs. Arsenal made sure of a crucial victory in the battle for Champions League qualification when Podolski crashed home his second goal of the night with 12 minutes left after a knockdown from Aaron Ramsey. After a slow start following their nerve-shredding penalty shoot-out win over Wigan at Wembley on Saturday, the Gunners went behind to a scrappy goal from Matt Jarvis on 40 minutes. However, German forward Podolski quickly levelled before half-time, with Giroud’s superb take-down and close-range finish putting them in front on 55 minutes. Olivier Giroud’s sublime finish and a double from Lukas Podolski gave FA Cup finalists Arsenal a 3-1 win over West Ham at the Emirates Stadium to move back up into the top four of the Barclays Premier League. Press Associationlast_img read more

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Department of Justice Awards $9.8 Million Grant to Parkland Victims

first_imgThe U.S. Department of Justice announced on Wednesday afternoon that it is awarding an Antiterrorism and Emergency Assistance Program grant of $9,801,224 to the victims of the 2018 mass shooting at Marjory Stoneman Douglas High School in Parkland.The funds will be distributed by the Florida Department of Legal Affairs’ Division of Victim Services and Criminal Justice Program to three recipients: the School Board of Broward County, Children’s Services Council of Broward County, and the United Way of Broward County, in collaboration with the City of Parkland and City of Coral Springs.In addition, agencies that provided services in the aftermath of the shooting will also receive some of the funds, as will students, families, staff and other members of the community who have been impacted by the shooting.“It has been more than two years since that tragic day, but the survivors and families of the victims will carry their emotional scars for many years to come,” Rep. Ted Deutch said. “I was so moved by the way our community rushed to help one another in the wake of the attack and has continued to provide mental health and wellness services to those still coping with the trauma.He continued, This grant is an acknowledgment that the survivors of this mass shooting, who have experienced unimaginable trauma, will need and deserve continued federal support to manage their pain and heal.”The funds for the grant come from the Crime Victims Fund, which is financed by fines and penalties that are paid by convicted federal offenders.last_img read more

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